Bill wants new blood on 'True Blood'

TV

Ree Hines TODAY contributor

14 hours ago

John P. Johnson / HBO

Stephen Moyer as vampire Bill Compton on "True Blood."

Three episodes into the season, and the action on "True Blood" -- like one vampire in particular -- is on fire.

The government's rounding up fangers, supes are fighting mad and Bill Compton is earning his big bad rep.

Everyone loves Eric
Viking vamp Eric Northman -- with his family and hostage Willa in tow -- said farewell to Fangtasia and hello to his old waitress-flunky-blood-donor-and-more, Ginger. She put up the bunch at her home and turned over a swanky coffin-for-two to Eric -- though she was gutted to learn he wouldn't share it with her. (Hey, at least she got a rain check!)

The lucky lady sharing his coffin was Willa, who seemed even happier to hear she'd be sleeping with Eric than she was to hear he wouldn't be killing her -- well, he wouldn't be killing her just yet.

As it turned out, the gov's little girl has info on daddy's vampire-torturing plans, and she's only too happy to spill it all without even getting glamoured first.

Werewolves without warnings
Over at the wolf pack, it seems Alcide is pack master in name only. When the cops came looking for Emma, it was Rikki who took charge, threatening the girl to get her shift into wolf form ... or else.

Then, when those pesky kids from Vampire Unity Society tried to get a glimpse at pack life, Alcide ordered his crew to stand down, but no one listened. Heck, he had to fight off Rikki just to leave one of them alive.

At least the others didn't die in vain. While they were busy getting slaughtered, Sam turned the distraction to his advantage and rescued little Emma.

Jason's back ?
Viewers who'd grown tired of the always-intense jerk Jason Stackhouse morphed into last season had something to celebrate Sunday night. After spending some quality time with his fairy grandpa, the old, sweet Jason finally returned.

Unfortunately, it was only a brief appearance.

Jason confessed the full extent of his recent bout of craziness to sister Sookie -- right down to the hate-filled hallucinations of their parents.

"You didn't wonder why I was acting all crazy and more racist than usual?" he asked her.

He just chalked it all up to what he assumed was another in a long line of concussions. But following a fresh walloping from Bill, Jason lost consciousness.

Bill wants blood
As for Bill, sure, vision-Lilith told him he's not a god, but the message hasn't really kicked in. Riding high on his uber-vamp transformation, Bill decided to give day-walking a try. The result? Flaming Bill.

Once Jessica put the fire out, Bill put his mind to his next big project: better-than-Tru-Blood. Now that the old blood substitute is off the shelves, he wants Tru Fairy Blood to take it's place.

To that end, he sent Jessica off to seduce the man behind the original brew, and then barged into Sookie's home -- no invite needed! -- to coax her into helping him out.

"You're not God, Bill. You're just an (expletive)," she informed him.

When Sookie declined, Bill delivered an emotional blow to her -- apparently, she's dead to him now -- and the aforementioned physical blow to her brother.

But that's not the end of his quest. When Bill found out that Andy Bellefleur now has a quartet of tween fairies, his eyes lit up.

Source: http://www.today.com/entertainment/bill-wants-new-blood-true-blood-6C10488686

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The ribosome: New target for antiprion medicines

July 2, 2013 ? New research results from Uppsala University, Sweden, show that the key to treating neurodegenerative prion diseases such as mad cow disease and Creutzfeldt-Jakob disease may lie in the ribosome, the protein synthesis machinery of the cell. The results were recently published in the Journal of Biological Chemistry.

Prion diseases are fatal neurodegenerative diseases caused by misfolding of prion proteins. Examples of prion diseases are scrapie in sheep, mad cow disease and Creutzfeldt-Jakob disease in human.

What triggers misfolding of the prion proteins to the amyloid disease form is an open question. The inadequate knowledge in the field about the factors involved in prion formation makes the discovery of effective medicines for prion diseases rather challenging.

"We have now shown that the protein folding activity of the ribosome (PFAR) is most likely involved in prion propagation and thus, can be a specific target for antiprion medicines. If we understand the mechanism fully, we will be able to find ways to stop that too.," says Suparna Sanyal, senior lecturer at the Department of Cell and Molecular Biology, Uppsala University .

The ribosome is the protein synthesis machinery of the cell. The mechanism of protein synthesis by the ribosome is well characterized, while PFAR is a rather recent discovery. PFAR is a ribosomal RNA dependent function of the large subunit of the ribosome irrespective of its source. The PFAR center closely overlaps the peptidyl transferase center although the nucleobases responsible for these two functions are not all common.

"Our results show that two prion inhibitors 6-aminophenanthridine and guanabenz acetate implement antiprion activity by binding to ribosomal RNA and inhibiting PFAR. Thus, the ribosome and more specifically PFAR is the new target for antiprion medicines. Furthermore, we have developed an in vitro PFAR assay, which can be used as a platform for screening prion inhibitors in a high-throughput fashion. This assay is much more time and cost-effective than standard prion assays," says Suparna Sanyal.

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Story Source:

The above story is reprinted from materials provided by Uppsala Universitet, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Y. Pang, S. Kurella, C. Voisset, D. Samanta, D. Banerjee, A. Schabe, C. Das Gupta, H. Galons, M. Blondel, S. Sanyal. The Antiprion Compound 6-Aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition. Journal of Biological Chemistry, 2013; 288 (26): 19081 DOI: 10.1074/jbc.M113.466748

Note: If no author is given, the source is cited instead.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/Rj_jDfOp4cM/130702100120.htm

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Captain Planet and the Planeteers Film Being Optioned by Sony

30
Jun
2013

Sony Pictures is looking at optioning the rights to the 1990?s animated series Captain Planet and the Planeteers.

I?ve said it before, but now I am truly convinced that Hollywood is completely out of ideas. While I am an unabashed fan of cartoons and watch them to this day, Captain Planet never caught my interest. I gave it a try, and while I?ve lived through cartoons such as Scooby-Doo Meets the Harlem Globetrotters, this series was just too far down the ladder for even me to watch.

That being said, for some?unknown?reason this 1900-1992 series is in play again for making a comeback. According to The Hollywood Reporter, Sony Pictures is in negotiations to acquire the rights, and making it even more mind boggling, it may be live-action.

Even if this option goes through, there is no guarantee it will see the light of day. There has already been an attempt at a film, but it never got past the script stage. And there has also been an attempt at a live-action TV series that never came?together.

If you are unfamiliar with the series ? and you should be grateful if you are ? five teenagers from around the world (North America, Africa, Eastern Europe, Asia and South America) are granted powers by Gaia, the Earth mother to protect the planet?s ecological system. When they come up against something they can?t overcome, they could combine their powers and summon Captain Planet.

While the heroes did take on villains such as?Looten Plunder, the series was just all about hitting you over the head with the ecological message. It was just? bad.

With this and Trolls in the work, you have to wonder if Hollywood has just given up.

[ Source The Hollywood Reporter ]

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Rogers To Receive Sony Xperia SP

By Ricardo Ribeiro on June 29th, 2013 0

?

Rogers will be adding another device to its Android line-up very soon. The new incomer is the Sony Xperia SP officially announced by Sony in March and as the name indicates packs some similarities with the former flagship Xperia S.

The Xperia SP comes with Android Jelly?Bean?4.1.2 and should see an upgrade to Android 4.2. As the Xperia?S?the SP also features a transparent ?light bar? that not only acts as a?notifier, but as?a mood light, matching the bar?s color to the colors on screen.

Spec wise the Xperia SP is?a LTE-enabled device packing a 4.6-inch 720p display. On the inside is a 1.7GHz dual-core processor with Adreno 320 graphics backed up by 1GB RAM which would make it a last year top-notch device. To hold all your files and music?you?ll?find 8GB of internal storage plus a microSD card slot for up to 32GB expansion. The phone also features an 8MP back camera and a front-facing VGA module.

The phone will come to Rogers in?Black, but pricing?details are scarce. Nonetheless, you should expect this device to launch within a few weeks.?A device launch?is always?good news, but is it a good enough addition to?Rogers? line-up? Leave your thoughts on the comment section below.

[Via Mobilesyrup]

Source: http://feedproxy.google.com/~r/androidincanada/~3/v-xW7i5FUHY/

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Triche looking at bright side heading into NBA Summer League

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SYRACUSE, N.Y. - After starting and winning more games at Syracuse University than anyone before him, Brandon Triche was understandably disappointed when he was not picked in the NBA Draft. But the Jamesville native is not about to give up.

Triche will get another chance to show he belongs in the NBA with the Charlotte Bobcats' summer team, which plays in the NBA Summer League in Las Vegas beginning July 17. His hope is to impress either Charlotte or another team enough to get a training camp invite.

Source: http://centralny.ynn.com/content/sports/671364/triche-looking-at-bright-side-heading-into-nba-summer-league

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Italo Calvino: Letters, 1941-1985

This collection of Calvino's letter unveils the correspondence of a writer at the heart of modern literature's revolutions.

June 30, 2013

Italo Calvino: Letters, 1941-1985 by Italo Calvino, Princeton University Press, 632 pages

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On?any list of writers who should have won the Nobel Prize but didn't, Italo Calvino would have to figure near the top, along with Nabokov and Borges. Calvino, who was born in 1923 and died in 1985, became famous in America mainly as the author of ludid, postmodernist works like?Invisible Cities ? a reworking of Marco Polo's travels, with a buried mathematical structure ? and?If on a winter's night a traveler,?a classic work of metafiction that continually stops and restarts itself while addressing the reader.?

But in his comparatively short life, Calvino played many roles in the literature of Italy and the world. Before he was a postmodernist, associated with the experiments of the Oulipo in Paris, he was a realist whose first successes were Hemingwayesque tales drawn from his own experience as a partisan fighter in Italy during World War II. He was also, starting with his partisan period, a Communist, striving to reconcile his intensely individual genius with the imperatives of the class struggle. When that proved impossible, after the Soviet invasion of Hungary in 1956, Calvino resigned from the Party, but he always considered himself a man of the Left.?

And from the very beginning of his career to the very end, he was also a publisher, associated with the leading Italian house of Einaudi. His work brought him into contact with just about every major Italian writer and cultural figure of the postwar period; many of them were his friends and collaborators, from Cesare Pavese and Carlo Levi to Michelangelo Antonioni and Pierpaolo Pasolini.

This intense activity, this committed and versatile service to letters, is the main impression that the reader takes away from?Italo Calvino: Letters, 1941-1985. A big book at nearly 600 pages, it still represents just a fraction of the correspondence published in Italian, and there are large areas of Calvino's life that go uncovered ? this is not one of those books of letters that can double as a biography.

There are no love letters included, for instance, nor anything to his parents or relatives; indeed, just about anything "personal" is left out. At the same time, Calvino writes in such granular detail about postwar Italian literature, with references to the titles, authors, characters, and plots of hundreds of works, that anyone who is not a specialist in that literature will probably feel a little adrift. (The notes, while numerous, are not nearly full enough for the general reader's purposes ? an adequately annotated edition would probably be twice as long.)?

Yet this austerity feels only appropriate for a man whose ideal way of life, he confides in one letter, would be to spend 12 hours a day reading. Several times in the "Letters," we hear Calvino dissuading people from trying to interview him or write his biography, on the grounds that ? as Barthes was saying around the same time ? the very idea of an "author" was dead, or should be: "To be able to study a writer, he must be?dead,?that is ? if he is alive ? he must be?killed? Furthermore, already the existence of the work is a sign that the author is?dead,?happily dead if the work is worthwhile; the work is the negation of the writer as empirical living being."?

Rather than an individual genius, Calvino wanted to be thought of as a member of a culture and a collective. "Life and works?" he writes to an Englishman proposing to devote a study to him. "I'm afraid I don't think I really have a?life?on which something can be written. All I have is a series of works that form part of the general context of literary works in our time. I am more and more convinced that literature is made up of works, genres, schools, discussions, problems, collective work in order to solve certain problems? If a critic writes about a problem and makes reference to one (or more) of my works in relation to that problem, this gives me the sense that my work is not pointless. Whereas the prospect of my bust crowned with laurel appearing along with the other busts in the hall of famous writers gives me no joy at all."?

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/rB5bURlTOjQ/Italo-Calvino-Letters-1941-1985

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Mayhem marks start of 100th Tour de France

BASTIA, Corsica (AP) ? Riders at the Tour de France know to expect the unexpected. But nothing could have prepared them for the mayhem that turned Saturday's first stage of the 100th Tour into a demolition derby on two wheels.

Seemingly for the first time at the 110-year-old race, one of the big buses that carry the teams around France when they're not on their bikes got stuck at the finish line, literally wedged under scaffolding, unable to move. The timing couldn't have been worse: The blockage happened as the speeding peloton was racing for home, less than 12 miles out.

Fearing the worst ? a possible collision between 198 riders and the bus ? race organizers took the split-second decision to shorten the race. Word went out to riders over their radios and they adapted tactics accordingly, cranking up their speed another notch to be first to the new line, now 1.8 miles closer than originally planned.

Then, somewhat miraculously, the bus for the Orica Greenedge team wriggled free. So organizers reverted to Plan A. Again over the radios, word went out to by-now confused riders and teams that the race would finish as first intended ? on a long straightaway alongside the shimmering turquoise Mediterranean, where an expectant crowd waited to cheer the first stage winner of the 100th Tour.

Then, bam! Two riders collided and one of them went down, setting off a chain of spills that scythed through the pack like a bowling ball.

And this was just Day One. The bad news for riders: They've still got another 20 stages and1,982 more miles to survive to the finish in Paris.

Keeping his head and riding his luck amid the chaos, Marcel Kittel sprinted for the win, claiming the first yellow jersey.

"It feels like I have gold on my shoulders," said the German rider for the Argos-Shimano team.

The 22 teams know from experience that the first days of any Tour are always tough. Everyone is nervous, full of energy and jostling for position. Adding to the stress this year is the race start in Corsica. The island's winding and often narrow roads that snake along idyllic coastlines and over jagged mountains are superbly telegenic but a worry for race favorites ? the likes of Team Sky's Chris Froome and two-time former champion Alberto Contador ? because a fall or big loss of time here could ruin their Tour before it really begins.

Froome survived Day One more or less unscathed. Contador didn't. The Spaniard, back at the Tour after a doping ban which also cost him his 2010 victory, crossed the line grimacing in pain, his left shoulder cut and bruised. He was tangled in the crash that threw about 20 riders to the tarmac. Contador said he'll be sore for a few days, "but I still have enough time to recover."

Even for the Tour, which has seen more than its fair share of dramas in 99 previous editions, Saturday's calamitous chain of events was exceptional.

"We've never had to change the finish line before," said Jean-Francois Pescheux, the event director who helps pick the route each year. "There's never been a bus stuck before."

The blockage at the line presented organizers with two solutions: cancel the stage entirely or shorten it, he said. They took the second option.

"We announced that in French, English, and Spanish on the Tour radio so that everybody was up-to-date," he said. Then, "in the following three minutes, we were told that the finish line was cleared. At that point, we announced that the finish was back to the real, original finish line."

Because of what Pescheux called "the little bout of panic and crashes" caused by this confusion, organizers subsequently decided to give everyone the same time as Kittel ? 4 hours, 56 minutes, 52 seconds over the 132-mile trek from the port town of Porto Vecchio to Bastia in the north of the island.

That means no one was penalized by Saturday's events.

"It's clear there was a moment of panic, and that's why we put everybody on equal footing," said Pescheux.

"The lesson learned is that buses, that heavy vehicles, they should avoid going through the finish line," he added.

"Everybody helped out, we deflated the tires of the bus so we could move it away as the peloton was fast approaching," said Jean-Louis Pages, who manages the finish-line area.

Organizers fined the Orica Greenedge team the equivalent of $2,100. The team's sporting director, Matt White, called the incident "really unfortunate."

"We took for granted that there was enough clearance. We've had this bus since we started the team, and it's the same bus we took to the Tour last year," he said. "Our bus driver was told to move forward and became lodged under the finish gantry."

Managers at other teams couldn't agree who to blame or be angry with most.

Marc Madiot of French team FDJ.FR was forgiving of the bus driver but furious with race organizers for changing their mind about where to finish the stage.

But the sporting director for Contador's Saxo-Tinkoff team, Philippe Mauduit, sided with the organizers.

"It's not the Tour's fault if there's a guy who doesn't know the height of his bus," he said.

"What caused the problems was changing the finish," said Mark Cavendish, the British sprinter who was counting on his great speed to win the stage but who instead was slowed by the crash. "It's just carnage."

His Omega Pharma-Quick Step teammate Tony Martin suffered concussion in the crash. Peter Sagan of Cannondale, another rider who was expecting to challenge for the win, finished with sticking plasters covering cuts on both legs and his left elbow. Other riders also suffered cuts and bruises. Froome's teammate Geraint Thomas flipped over his handlebars and "really whacked the back of his pelvis," said Dave Brailsford, the Team Sky manager.

"The goal for us is to get off this island in one piece, having lost no time," he said. "It's a much tougher ask than it may seem."

"You don't know what's going to happen. But you know something is going to happen," he added.

Perhaps as soon again as Sunday. The tricky second stage features four climbs along the 97-mile ride from Bastia to Ajaccio, crossing the island's mountainous spine.

Before Saturday's stage, French Sports Minister Valerie Fourneyron met with a delegation of riders unhappy that pre-race media coverage of the race dwelt heavily on doping in cycling.

That was partly the fault of Lance Armstrong. The disgraced former champion now stripped of his seven Tour wins caused a stir by telling Le Monde that he couldn't have won the race without doping.

___

AP Sports Writer Jerome Pugmire and Associated Press writer Jamey Keaten contributed to this report.

Source: http://news.yahoo.com/mayhem-marks-start-100th-tour-france-210626611.html

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